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Lillian Eva Quan Dyck, OC, scholar, feminist, senator, advocate for Indigenous rights (born 24 August 1945 in North Battleford, SK). Lillian Dyck was the first Indigenous woman in Canada to earn a PhD in science. She was also the first Indigenous female senator and the first Chinese Canadian senator. During her time in the Senate, she was part of several actions to improve life for Indigenous people in Canada. This includes work on criminal justice and Indigenous education reform, and bills to reinstate Indian Status to women who had lost it based on sexist laws. Dyck was made an Officer of the Order of Canada in 2021.

Laurent “Dr. Kill” Duvernay-Tardif, CQ, football player, doctor (born 11 February 1991 in Saint-Jean-Baptiste, QC). Laurent Duvernay-Tardif is an offensive lineman with the New York Jets of the National Football League (NFL). He was the 10th player ever drafted into the NFL from Canadian college and university football, and is the first Quebec-born football player to win a Super Bowl championship. Duvernay-Tardif is also the first active NFL player to become a doctor. He opted out of the 2020 season to work at a Montreal long-term care facility during the COVID-19 pandemic. He was made a Chevalier of the Ordre national du Québec in 2019. In 2020, he was named a Sportsperson of the Year by Sports Illustrated, as well as co-winner (with soccer player Alphonso Davies) of the Lou Marsh Trophy as Canada’s athlete of the year.

Allan Selwyn Bundy, pilot (born 1920 in Dartmouth, NS; died 9 December 2001 in Toronto, ON). He was one of two known Black Canadian combat pilots during the Second World War. Bundy served in the Royal Canadian Air Force (RCAF) and, according to the operations record book of 404 Squadron, flew 28 combat missions.

Judie Barbara Alimonti, immunologist (born 13 March 1960 in Kelowna, BC; died 26 December 2017 in Ottawa, ON). Alimonti made a significant contribution to one of Canada’s greatest achievements in medical science and public health, the development of the Ebola vaccine. (See also Medical Research.) From 2010 to 2015, Alimonti managed the Ebola vaccine during a time when research was underfunded. Alimonti received little recognition for her work during her lifetime, and her colleagues have called her the unsung hero of the Ebola vaccine story.

Werner Israel, OC, FRS, FRSC, physicist (born 4 October 1931 in Berlin, Germany; died 18 May 2022 in Victoria, BC). Werner contributed new insights to the field of physics and is perhaps best known for his research on black holes. During his career, he collaborated with the English physicist Stephen Hawking.

Henri Joseph Breault, medical doctor, anti-poisoning advocate (born 4 March 1909 in Tecumseh, ON; died 5 September 1983 in Exeter, ON). Breault is known for spearheading a national campaign to prevent accidental childhood poisonings. He advocated for the development of the Palm-N-Turn, a safety cap that drastically reduced child deaths due to poisoning in Canada and around the world.

David Ernest Hornell, VC, clerk, pilot (born 26 January 1910 in Toronto, Ontario; died 25 June 1944 at sea near the Faroe Islands in the North Atlantic Ocean). During the Second World War, Hornell was awarded a posthumous Victoria Cross (VC) for his heroic actions in sinking a German submarine and encouraging his crewmates after their plane was shot down. He was the first member of the Royal Canadian Air Force (RCAF) to receive the VC.

Jean Coutu, O.C., O.Q., pharmacist, entrepreneur and philanthropist (born 29 May 1927 in Montreal, Quebec). Jean Coutu is the founder of the Jean Coutu Group, a chain of pharmacies established in 1969 under the name Pharm-Escomptes Jean Coutu. He is also the cofounder of the Marcelle and Jean Coutu Foundation, a private charitable foundation. Jean Coutu has received many honours and awards recognizing both his career and his philanthropy.

Wilder Graves Penfield, OM, CC, FRS, FRSC neurosurgeon, scientist (born 26 January 1891 in Spokane, Washington; died 5 April 1976 in Montreal, QC). Dr. Penfield was the founder and first director of the Montreal Neurological Institute and established the "Montreal procedure" for the surgical treatment of epilepsy. (See also Neuroscience.)

Nadine Rena Caron, OBC, surgeon, researcher, mentor, educator, patient advocate, community leader (born 1970 in Kamloops, BC). Nadine Caron was the first female First Nations student to graduate from the University of British Columbia Faculty of Medicine. She was also the first female First Nations general surgeon in Canada. For many years, Caron has highlighted the needs and voices of northern, rural and Indigenous populations in Canada.

Flordeliz (a.k.a. Gigi) Osler (née Sharma), FRCSC, senator, physician and educator (born 1968 in Winnipeg, MB). Dr. Osler is an Otolaryngology – Head and Neck surgeon (ENT) surgeon and has practiced in Winnipeg since 1998. She was the past president of the Canadian Medical Association, making her the first female surgeon and the first woman of colour to assume the role. Osler was appointed to the Canadian Senate in 2022, making her the second senator of Filipino descent and the first woman of Filipino heritage to sit in the Senate.

Dominique François Gaspard, physician and community builder (born 22 December 1884 in New Orleans, Louisiana; died 6 February 1938 in Montreal, QC). Gaspard was a respected doctor and a trailblazer in Montreal’s Black district. After serving with distinction at a field hospital during the First World War, he devoted himself to medical practice in Montreal. He also worked to create social and intellectual outlets for Black men in the city. A bilingual Catholic, he was unique in the city’s early-20th-century anglophone Protestant Black community. His story speaks of a complexity of language, ethnicity and migration not often explored in narratives of Quebec’s English-speaking and Black communities.

Robert Baird McClure, CM, OOnt, medical missionary, moderator United Church of Canada (born 23 November 1900 in Portland, OR; died 10 November 1991 in Toronto, ON). As a medical missionary, McClure provided medical care and services in numerous countries, including China, Egypt and India. He was elected a lay moderator of the United Church of Canada in 1968. McClure received numerous honours and awards in recognition of his services.

Marc Garneau, CC, astronaut, military officer, engineer, politician (born 23 February 1949 in Québec City, QC). Garneau has distinguished himself in three distinct fields. As a naval officer with the Canadian Armed Forces, he spent 10 years as a combat systems engineer. In 1984, Garneau became the first Canadian astronaut to go to space and, from 2001 to 2005, was president of the Canadian Space Agency. As a federal politician, he has served as Liberal house leader, minister of transport and minister of foreign affairs.

COVID-19 vaccines were the first vaccines to be developed, tested, produced and delivered amid a global pandemic (see Covid-19 Pandemic in Canada). As the typical vaccine development, testing and regulatory approval process can take anywhere from 10 to 15 years, several distinctive strategies, coupled with previous research work in key areas, combined to expedite the approval of COVID-19 vaccines, especially messenger ribonucleic acid (mRNA)-based vaccines. Among the most significant of this previous work was the research undertaken by the team of Pieter Cullis, Michael Hope and Thomas Madden at the University of British Columbia that began in the early 1980s. Their work, which focused on studying and developing lipid nanoparticles (LNPs), as well as pioneering the technology to produce them, provided the key to making COVID-19 mRNA vaccines possible.

An astronaut is an individual involved in flight beyond the Earth’s atmosphere. Since the National Research Council of Canada held its first recruitment campaign in 1983, 14 Canadians have completed astronaut training and nine have participated in 17 missions to space. Specifically, they have flown as payload specialists, mission specialists, and flight engineers on NASA shuttle flights and expeditions to the International Space Station (ISS). Canadian astronauts have played key roles in repairing satellites and building the ISS using the Canadarm and Canadarm2 robotic technologies, and have advanced scientific knowledge by conducting a variety of experiments in space. (See also Robotics in Canada; Space Technology.)